Influence of variation of the serum creatinine on outcomes of patient with acute kidney injury

Keywords: Acute Kidney Injury; Creatinine; Mortality.1Universidade de Brasília. Brasília, DF, Brasil.Autor correspondente: Tayse Tâmara da Paixão DuarteFaculdade de Ceilândia – Universidade de Brasília.Departamento de Enfermagem.Centro Metropolitano, conjunto A, lote 01. CEP: 72220-900. Brasília, DF, Brasil. E-mail:


Objective: to identify the influence of variations on serum creatinine on outcomes of patients with acute kidney failure. Methods: observational and prospective study. Eighty-five patients which evolved with renal impairment composed the sample. The data was extracted from medical records and reported in a questionnaire created previously. It was considered values p≤0.05 as significant. Results: most of patients were male gender (51.8%) and elder (66±14 years). The reduction of kidney function occurred in different graduation, considering that 35.3% evolved with risk to kidney injury (stage 1) and lower percentage (14.1%) was more severely affected (stage 2 and 3), respectively. During follow-up, the clearance creatinine progressively increased showing recovery of kidney function. Patients with renal injury or failure (stage 2 or 3) evolved more frequently to death (p=0,027). Conclusion: variations on serum creatinine may exacerbate the patient outcomes over hospitalization period.


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Research Article