Diabetes mellitus and severity by COVID-19 in hospitalized Brazilians

Keywords: Diabetes Mellitus; Coronavirus Infections; Hospitalization; Severity of Illness Index; Cross-Sectional Studies.

Abstract

Objective: to estimate the prevalence of severity of hospitalized cases of COVID-19 and its association with diabetes mellitus. Methods: a cross-sectional study, which used secondary data from the Influenza Epidemiological Surveillance Information System, totaling 405,294 confirmed cases. To verify the association of diabetes and severity in hospitalized patients with COVID-19, Poisson regression models with robust variance estimator were used. Initially, the association of disease with outcome was verified; next, several adjustments for potential confounders were performed. Results: the prevalence of diabetes in the 405,294 hospitalized and positive cases was 25.7% (Confidence Interval: 25.5% - 25.8%). After adjustments, diabetes was found to increase the severity of COVID-19 by 19% (Confidence Interval: 1.17 - 2.21). Conclusion: a significant association of diabetes mellitus with severe cases of COVID-19 infection has been identified. Contributions to practice: the evidence generated by the study guides the risk stratification of patients and directs clinical management.


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Published
2022-09-20
How to Cite
Garces, T. S., Sousa, G. J. B., Cestari, V. R. F., Mattos, S. M., Florêncio, R. S., Pereira, M. L. D., & Moreira, T. M. M. (2022). Diabetes mellitus and severity by COVID-19 in hospitalized Brazilians. Rev Rene, 23, e81354. https://doi.org/10.15253/2175-6783.20222381354
Section
Research Article