TY - JOUR AU - Borges, Eline Lima AU - Spira, Josimare Aparecida Otoni AU - Amorim, Gilmara Lopes AU - Coelho, Ana Carolina Silva Martins PY - 2022/04/13 Y2 - 2024/03/28 TI - Biofilm formation in cutaneous wounds and its behavior in the face of interventions: an integrative review JF - Rev Rene JA - Rev Rene VL - 23 IS - 0 SE - Review Article DO - 10.15253/2175-6783.20222378112 UR - http://www.periodicos.ufc.br/rene/article/view/78112 SP - e78112 AB - <p><strong>Objective:</strong> to identify in the literature the biofilm formation and its behavior when faced with interventions in cutaneous wounds. <strong>Methods:</strong> an integrative review, carried out in the Cumulative Index to Nursing and Allied Health Literature, Latin American and Caribbean Health Sciences Literature, EMBASE, Scopus, The Cochrane Library Collaboration, MEDLINE/PubMed and Science Direct databases, without temporal delimitation. Nineteen studies were selected. The information was evaluated descriptively, comparing it with the pertinent findings. <strong>Results:</strong> the sample studies were published in English and included three types of biofilm research: two clinical, six in vitro and 11 in vivo (animal). Three themes were included: biofilm model creation (n=4), biofilm assessment (n=3), biofilm behavior before interventions for its management (n=12). <strong>Conclusion:</strong> the detrimental effects of biofilm on wound healing have been confirmed. Several interventions were able to reduce and eliminate biofilm in in vitro and in vivo models.<strong> Contributions to practice:</strong> it was found that clinical evaluation of the lesion does not allow the identification of biofilm, even when present; it is below the surface of the lesion. This finding raises reflection on the part of nurses regarding the interventions adopted for the removal of biofilm.</p> ER -