TY - JOUR AU - Garces, Thiago Santos AU - Sousa, George Jó Bezerra AU - Cestari, Virna Ribeiro Feitosa AU - Mattos, Samuel Miranda AU - Florêncio, Raquel Sampaio AU - Pereira, Maria Lúcia Duarte AU - Moreira, Thereza Maria Magalhães PY - 2022/09/20 Y2 - 2024/03/28 TI - Diabetes mellitus and severity by COVID-19 in hospitalized Brazilians JF - Rev Rene JA - Rev Rene VL - 23 IS - 0 SE - Research Article DO - 10.15253/2175-6783.20222381354 UR - http://www.periodicos.ufc.br/rene/article/view/81354 SP - e81354 AB - <p><strong>Objective</strong>: to estimate the prevalence of severity of hospitalized cases of COVID-19 and its association with diabetes mellitus. <strong>Methods</strong>: a cross-sectional study, which used secondary data from the Influenza Epidemiological Surveillance Information System, totaling 405,294 confirmed cases. To verify the association of diabetes and severity in hospitalized patients with COVID-19, Poisson regression models with robust variance estimator were used. Initially, the association of disease with outcome was verified; next, several adjustments for potential confounders were performed. <strong>Results</strong>: the prevalence of diabetes in the 405,294 hospitalized and positive cases was 25.7% (Confidence Interval: 25.5% - 25.8%). After adjustments, diabetes was found to increase the severity of COVID-19 by 19% (Confidence Interval: 1.17 - 2.21). <strong>Conclusion</strong>: a significant association of diabetes mellitus with severe cases of COVID-19 infection has been identified. <strong>Contributions to practice</strong>: the evidence generated by the study guides the risk stratification of patients and directs clinical management.</p> ER -