Evaluation of the quality of life of cancer patients undergoing chemotherapy

Keywords: Quality of Life; Medical Oncology; Drug Therapy.


Objective: to assess the quality of life of cancer patients undergoing chemotherapy. Methods: a cross-sectional study carried out in the chemotherapy sector with 51 patients able to answer the data collection instruments. For the analyses, we adopted the variance analysis and Student’s t. Results: the health score indicated moderate quality of life and the symptoms nausea and vomiting, diarrhea, and dyspnea were the most present. The scores of the global health scale showed differences between age groups and presence of metastasis; diarrhea and financial difficulties showed differences with respect to gender; pain was more cited by those who did not undergo surgery; insomnia and nausea and vomiting were related to the time of treatment. Conclusion: participants had moderate overall health scores and the main functional levels affected by the treatment were social and emotional.


Taylor T, Al-Mossawi H, The principles of neoplasia and oncology. Surgery. 2017; 36(3):99-105. doi: https://doi.org/10.1016/j.mpsur.2017.12.007

Bray F, Ferlay J, Soerjomataram I, Siegel RL, Torre LA, Jemal A. Global cancer statistics 2018: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries. Cancer J Clin. 2018; 68(6):394-424. doi: https://doi.org/10.3322/caac.21492

Ministério da Saúde (BR). DATASUS. Mortalidade por residência por capítulo de CID [Internet]. 2019 [cited May 20, 2021]. Available from: http://tabnet.datasus.gov.br/cgi/tabcgi.exe?sim/cnv/obt10uf.def

Instituto Nacional de Câncer José Alencar Gomes da Silva. Coordenação de Prevenção e Vigilância. Estimativa 2020: incidência de câncer no Brasil. Rio de Janeiro: INCA; 2019.

Sung H, Ferlay J, Siegel RL, Laversanne M, Soerjomataram I, Jemal A, et al. Global cancer statistics 2020: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries. CA Cancer J Clin. 2021; 71(3):209-49. doi: https://doi.org/10.3322/caac.21660

Miller KD, Nogueira L, Mariotto AB, Rowland JH, Yabroff KR, Alfano CM, et al. Cancer treatment and survivorship statistics, 2019. CA Cancer J Clin. 2019; 69(5):363-85. doi: https://doi.org/10.3322/caac.21565

Dickens E, Ahmed S. Principles of cancer treatment by chemotherapy. Surgery. 2018; 36(3):134-8. doi: https://doi.org/10.1016/j.mpsur.2017.12.002

Freire MEM, Costa SFG, Lima RAG, Sawada NO. Health-related quality of life of patients with cancer in palliative care. Texto Contexto Enferm. 2018; 27(2):e5420016. https://dx.doi.org/10.1590/0104-070720180005420016

Caldini LN, Medina LA, Silva RA, Barros LM, Lima MM, Melo GA, et al. Self-concept and role function in patients with head and neck cancer. Acta Paul Enferm. 2021; 34:eAPE00892. doi: https://doi.org/10.37689/acta-ape/2021AO00892

Douberin CA, Silva LSR, Matos DP, Mendes Filho EB, Cordeiro EL, Barbosa MF, et al. Main comorbidities associated with breast neoplasia in chemotherapeutic treatment. Rev Enferm UFPE on line [Internet]. 2019 [cited May 20, 2021]; 13(5):1295-9. Available from: https://periodicos.ufpe.br/revistas/revistaenfermagem/article/view/238540

Arantes TC, Martins VE, Mendes AS, Silva AMB, Nicolussi AC. Factors associated with depression in cancer patients during chemotherapy. Rev Rene. 2019; 20:e41647. doi: http://dx.doi.org/10.15253/2175-6783.20192041647

Silveira FM, Wysocki AD, Mendez RD, Pena SB, Santos EM, Malaguti-Toffano S, et al. Impact of chemotherapy treatment on the quality of life of patients with cancer. Acta Paul Enferm. 2021; 34:eAPE00583. doi: http://dx.doi.org/10.37689/actaape/2021AO00583

Souza JC, Santos EGA, Santos ALS, Santos MIPO, Fernandes DS, Oliveira TNC. Quality of life of elderly patients submitted to antineoplastic chemothe- rapy treated at an oncology reference hospital. Rev Pan-Amaz Saude. 2018; 9(3):47-55. doi: https://doi.org/10.5123/S2176-62232018000300006

Aaronson NK, Ahmedzai S, Bergman B, Bullinger M, Cull A, Duez NJ, et al. The European Organization for Research and Treatment of Cancer QLQ-C30: a quality of life instrument for use in international clinical trials in oncology. J Natl Cancer Inst. 1993; 85(5):365-76. doi: https://doi.org/10.1093/jnci/85.5.365

Silva IBS, Lima Júnior JRM, Almeida JS, Cutrim DS, Sardinha AHL. Evaluation of the quality of life of oncological patients in palliative care. Rev Bras Cancerol. 2020; 66(3):e-121122. doi: https://doi.org/10.32635/2176-9745.RBC.2020v66n3.1122

Carmona-Bayonas A, Calderón C, Hernández R, Montes AF, Castelo B, Ciria-Suarez L, et al. Prediction of quality of life in early breast cancer upon completion of adjuvant chemotherapy. NPJ Breast Cancer. 2021; 7(1):92. doi: https://doi.org/10.1038/s41523-021-00296-8

Lewandowska A, Rudzki G, Lewandowski T, Próchnicki M, Rudzki S, Laskowska B, et al. Quality of life of cancer patients treated with chemotherapy. Int J Environ Res Public Health. 2020; 17(19):6938. doi: https://doi.org/10.3390/ijerph17196938

How to Cite
Carlos, E. A., Borgato, J. A., & Garbuio, D. C. (2022). Evaluation of the quality of life of cancer patients undergoing chemotherapy. Rev Rene, 23, e71133. https://doi.org/10.15253/2175-6783.20222371133
Research Article